BDBM50581530 CHEMBL5086911

SMILES CC(C)c1ccc(cc1)[C@@H](c2[nH]c3cc(ccc3n2)C(=O)O)OC

InChI Key InChIKey=PVZNGPPPFPTWEL-UHFFFAOYSA-N

Data  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50581530   

TargetMixed lineage kinase domain-like protein(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50581530(CHEMBL5086911)
Affinity DataKd:  5.00E+4nMAssay Description:Binding affinity to MLKL N-terminal executioner domain (2 to 154 residues)(unknown origin) assessed as dissociation constant by TROSY-HSQC NMR titrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMixed lineage kinase domain-like protein(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50581530(CHEMBL5086911)
Affinity DataKd:  2.15E+5nMAssay Description:Binding affinity to MLKL N-terminal executioner domain (2 to 154 residues)(unknown origin) assessed as dissociation constant in presence of Nonyl-mal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)