BDBM50581233 CHEMBL5091510

SMILES Cc1nc(OCc2ccsc2)c2c(c[nH]c2n1)-c1ccnc(N)c1

InChI Key InChIKey=BWRQNVDGLTUELI-UHFFFAOYSA-N

Data  7 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50581233   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Vernalis (R&D)

Curated by ChEMBL

LigandBDBM50581233(CHEMBL5091510)Copy SMILESCopy InChI

Affinity DataIC50: 6nMAssay Description:Inhibition of DYRK1A (unknown origin) assessed as accumulation of ADP by ADP hunter plus assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/5/2023
Entry Details Article
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TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Vernalis (R&D)

Curated by ChEMBL

LigandBDBM50581233(CHEMBL5091510)Copy SMILESCopy InChI

Affinity DataIC50: 9nMAssay Description:Inhibition of DYRK1A (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/5/2023
Entry Details Article
Copy Entry DOIPubMed
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TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
Vernalis (R&D)

Curated by ChEMBL

LigandBDBM50581233(CHEMBL5091510)Copy SMILESCopy InChI

Affinity DataIC50: 1nMAssay Description:Inhibition of DYRK1B (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/5/2023
Entry Details Article
Copy Entry DOIPubMed
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TargetCyclin-dependent kinase 9(Human)
Vernalis (R&D)

Curated by ChEMBL

LigandBDBM50581233(CHEMBL5091510)Copy SMILESCopy InChI

Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CDK9 (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/5/2023
Entry Details Article
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TargetSerine/threonine-protein kinase pim-1(Human)
Vernalis (R&D)

Curated by ChEMBL

LigandBDBM50581233(CHEMBL5091510)Copy SMILESCopy InChI

Affinity DataIC50: 79nMAssay Description:Inhibition of PIM1 (unknown origin) by ADP hunter plus assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/5/2023
Entry Details Article
Copy Entry DOIPubMed
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TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Vernalis (R&D)

Curated by ChEMBL

LigandBDBM50581233(CHEMBL5091510)Copy SMILESCopy InChI

Affinity DataIC50: 8nMAssay Description:Inhibition of DYRK2 (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/5/2023
Entry Details Article
Copy Entry DOIPubMed
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TargetDual specificity protein kinase CLK1(Human)
Vernalis (R&D)

Curated by ChEMBL

LigandBDBM50581233(CHEMBL5091510)Copy SMILESCopy InChI

Affinity DataIC50: 17nMAssay Description:Inhibition of CLK (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/5/2023
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL