BDBM50575977 CHEMBL4859703

SMILES Cc1cc(=O)n2nc(c(-c3ccccc3)c2[nH]1)-c1ccccc1

InChI Key InChIKey=BMPPFRFXVLJIEW-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50575977   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Agios Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50575977(CHEMBL4859703)
Affinity DataKd:  7.00E+4nMAssay Description:Binding affinity to MAT2A (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Agios Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50575977(CHEMBL4859703)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of MAT2A (unknown origin) mass spectrometry-based ultrafiltration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Agios Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50575977(CHEMBL4859703)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed