BDBM50574222 CHEMBL4856516

SMILES c1cc(c(cc1F)CNc2ncc(c(n2)NC3CCCC3)C(=O)NCCCN4CCCC4=O)F

InChI Key InChIKey=CGCYACANDHXNLI-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50574222   

TargetPeripheral plasma membrane protein CASK(Human)
Goethe University Frankfurt Am Main

Curated by ChEMBL
LigandPNGBDBM50574222(CHEMBL4856516)
Affinity DataKd:  630nMAssay Description:Binding affinity to recombinant N-terminal His-tagged CASK (1 to 337 residues) (unknown origin) expressed in Escherichia coli assessed as dissociatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Goethe University Frankfurt Am Main

Curated by ChEMBL
LigandPNGBDBM50574222(CHEMBL4856516)
Affinity DataIC50: 4.48E+3nMAssay Description:Inhibition of tracer K5 binding to NanoLuc-fused MERTK (unknown origin) expressed in HEK293T cells measured after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)