BDBM50569657 CHEMBL4863492

SMILES CN1CCc2cc(c(cc2C1)Nc3ncc(c(n3)Nc4ccccc4Br)C(=O)N)OC

InChI Key InChIKey=SDKKHBKWXKHEHO-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50569657   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Merck

Curated by ChEMBL

LigandBDBM50569657(CHEMBL4863492)Copy SMILESCopy InChI

Affinity DataIC50: 0.0940nMAssay Description:Inhibition of HPK1 (unknown origin) using SLP76 as substrate incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
8/20/2022
Entry Details Article
Copy Entry DOIPubMedPDB3D Structure (crystal)
Copy Rxn URL