BDBM50562112 CHEMBL4743888

SMILES CC1(c2ccc(cc2N(C1=O)Cc3c(cccc3Cl)F)C(=O)NCc4c(cc(cc4F)F)F)C

InChI Key InChIKey=OEBVYNULNKSONR-UHFFFAOYSA-N

Data  3 EC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50562112   

TargetStimulator of interferon genes protein(Human)
Curadev Pharma

Curated by ChEMBL
LigandPNGBDBM50562112(CHEMBL4743888)
Affinity DataEC50:  185nMAssay Description:Activation of wild-type human STING expressed in HEK293T cells assessed as IRF3 reporter activation measured after 20 hrs by luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
Curadev Pharma

Curated by ChEMBL
LigandPNGBDBM50562112(CHEMBL4743888)
Affinity DataEC50:  185nMAssay Description:Agonist activity at human STINGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
Curadev Pharma

Curated by ChEMBL
LigandPNGBDBM50562112(CHEMBL4743888)
Affinity DataEC50:  185nMAssay Description:Agonist activity at human STING in HEK293T cells by luciferase cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)