BDBM50560976 CHEMBL4747278

SMILES Cn1c(cc2c1c(ccc2Nc3cccc(c3)OC)Cl)C(=O)NS(=O)(=O)c4ccc(cc4)OC

InChI Key InChIKey=JEHVWVLILUTLQN-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50560976   

TargetFructose-1,6-bisphosphatase 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50560976(CHEMBL4747278)
Affinity DataIC50: 52nMAssay Description:Inhibition of human liver FBPase expressed in Escherichia coli BL21(DE3) using FBP as substrate in presence of PGI and G6PDH by spectrophotometric me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)