BDBM50559311 CHEMBL4780011

SMILES CCN(CC)S(=O)(=O)c1ccc(c(c1)NC(=O)c2c3c(c([nH]2)C)C(=O)CCCC3)OC

InChI Key InChIKey=DLOWILGTRNUHPQ-UHFFFAOYSA-N

Data  3 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50559311   

TargetBromodomain-containing protein 4(Human)
Albert-Ludwigs-Universit£T Freiburg

Curated by ChEMBL
LigandPNGBDBM50559311(CHEMBL4780011)
Affinity DataKd:  140nMAssay Description:Binding affinity to BRD4 BD1 (unknown origin) at 25 degree C by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
Albert-Ludwigs-Universit£T Freiburg

Curated by ChEMBL
LigandPNGBDBM50559311(CHEMBL4780011)
Affinity DataKd:  85nMAssay Description:Binding affinity to human BRD4 BD1 (N44 to E168 aa residues) by bromoKdELECT Discover assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 9(Human)
Albert-Ludwigs-Universit£T Freiburg

Curated by ChEMBL
LigandPNGBDBM50559311(CHEMBL4780011)
Affinity DataKd:  160nMAssay Description:Binding affinity to human partial length BRD9 (R130 to V259 residues) by bromoKdELECT Discover assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed