BDBM50557391 CHEMBL4745155::US20240140952, Compound 3

SMILES C=CCCn1cc(cn1)-c1nc(Nc2ccc(cc2)C2CCNCC2)nc2[nH]ccc12

InChI Key InChIKey=OZUDWDBQZJPKOG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50557391   

TargetTyrosine-protein kinase JAK2(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM50557391(CHEMBL4745155 | US20240140952, Compound 3)
Affinity DataIC50: 0.260nMAssay Description:Inhibition of human JAK2 by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM50557391(CHEMBL4745155 | US20240140952, Compound 3)
Affinity DataIC50: 0.260nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
Go to US Patent