BDBM50557388 CHEMBL4743499::US20240140952, Compound (S)-1

SMILES N#CC[C@@H](C1CCCC1)n1cc(cn1)-c1nc(Nc2ccc(cc2)C2CCNCC2)nc2[nH]ccc12

InChI Key InChIKey=RGIJZWRVCBSGJV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50557388   

TargetTyrosine-protein kinase JAK2(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM50557388(CHEMBL4743499 | US20240140952, Compound (S)-1)
Affinity DataIC50: 0.0990nMAssay Description:Inhibition of human JAK2 by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM50557388(CHEMBL4743499 | US20240140952, Compound (S)-1)
Affinity DataIC50: 0.0990nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
Go to US Patent