BDBM50552926 CHEMBL4791214

SMILES c1cc(cc(c1)Cl)C(=O)N2CCCc3c2ccc(c3)CNC(=O)c4ccc(cc4)Cl

InChI Key InChIKey=XCOPXJUWALYDIJ-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50552926   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck

Curated by ChEMBL

LigandBDBM50552926(CHEMBL4791214)Copy SMILESCopy InChI

Affinity DataIC50: 9nMAssay Description:Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as reduction in kynurenine production using L-Tryptophan as substrate incubated ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
3/24/2022
Entry Details Article
Copy Entry DOIPubMedPDB3D Structure (crystal)
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck

Curated by ChEMBL

LigandBDBM50552926(CHEMBL4791214)Copy SMILESCopy InChI

Affinity DataIC50: 1.10E+4nMAssay Description:Displacement of [35S]-MK499 binding to human ERG expressed in HEK293 cells incubated for 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
3/24/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL