BDBM50552551 CHEMBL4784974

SMILES CC(C)c1cc(ccc1OC)Oc2c(cc(cc2Cl)NC(=O)Cc3cccnc3)Cl

InChI Key InChIKey=NSQNWKUVCNRXBW-UHFFFAOYSA-N

Data  2 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50552551   

TargetNuclear receptor ROR-gamma(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50552551(CHEMBL4784974)
Affinity DataEC50:  34nMAssay Description:Agonist activity at Gal4-fused RORgammat (unknown origin) expressed in Jurkat cells by reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetThyroid hormone receptor beta(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50552551(CHEMBL4784974)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human TRbeta1 CHO-K1 cells by reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed