BDBM50549942 CHEMBL4748121

SMILES Cc1c[nH]c2ncc(cc12)-c1c[nH]c2C(=O)NCc12

InChI Key InChIKey=WKBTUQDWSZYQRW-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50549942   

TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50549942(CHEMBL4748121)
Affinity DataKd:  5.10E+3nMAssay Description:Binding affinity to folded P-loop conformation of wild type N-terminal NH-tagged and avi-tagged dephosphorylated human c-MET (956 to 1390 residues) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50549942(CHEMBL4748121)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of wild type N-terminal NH-tagged and avi-tagged dephosphorylated human c-MET (956 to 1390 residues) expressed in Sf21 cells using poly (G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed