BDBM50549941 CHEMBL4744343

SMILES c1ccc(cc1)Cc2c[nH]c3c2cccn3

InChI Key InChIKey=GZMFYYLEABBTHR-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50549941   

TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50549941(CHEMBL4744343)
Affinity DataKd:  9.70E+4nMAssay Description:Binding affinity to folded P-loop conformation of wild type N-terminal NH-tagged and avi-tagged dephosphorylated human c-MET (956 to 1390 residues) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50549941(CHEMBL4744343)
Affinity DataIC50: 2.42E+4nMAssay Description:Inhibition of wild type N-terminal NH-tagged and avi-tagged dephosphorylated human c-MET (956 to 1390 residues) expressed in Sf21 cells using poly (G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)