BDBM50548815 CHEMBL4790845

SMILES Cc1nnn(n1)Cc2cc(ccc2/C=C/C(=O)N3CCN(C[C@H]3C)Cc4ccc(cc4)F)Cl

InChI Key InChIKey=VZLIOCMTERNIPD-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50548815   

TargetAutotaxin(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50548815(CHEMBL4790845)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of human recombinant ATX expressed in HEK293 cells assessed as inhibition of choline release using LPC (18:1) as substrate preincubated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)