BDBM50546407 CHEMBL4740065

SMILES Cn1ccc2c(cccc12)-c1nc2c(ccnc2[nH]1)-n1cc(N[C@@H]2CCOC[C@@H]2N)cn1

InChI Key InChIKey=MXZJNQSPLXUEQL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50546407   

LigandPNGBDBM50546407(CHEMBL4740065)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50546407(CHEMBL4740065)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50546407(CHEMBL4740065)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandPNGBDBM50546407(CHEMBL4740065)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of human ERG assessed as tail current by plate-based planar patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed