BDBM50546335 CHEMBL4755577

SMILES c1ccc(cc1)CNc2c3c(ncn2)n(cn3)[C@H]4[C@@H]([C@@H]([C@H](O4)COP(=O)(CP(=O)(O)O)O)O)O

InChI Key InChIKey=DMBYYIJBPDWQFF-UHFFFAOYSA-N

Data  2 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50546335   

Target5'-nucleotidase(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546335(CHEMBL4755577)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human CD73More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5'-nucleotidase(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546335(CHEMBL4755577)
Affinity DataKi:  2.20nMAssay Description:Inhibition of human recombinant soluble CD73 assessed as inhibition constant by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5'-nucleotidase(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546335(CHEMBL4755577)
Affinity DataKi:  2.20nMAssay Description:Binding affinity to human recombinant CD73 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)