BDBM50542679 CHEMBL4639584

SMILES c1cc(c(cc1NC(=O)CS)Cl)Cl

InChI Key InChIKey=OXXGBQLQQBKIJO-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50542679   

TargetElastase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips) - Helmholtz Centre For Infection Research (Hzi

Curated by ChEMBL
LigandPNGBDBM50542679(CHEMBL4639584)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa PA14 LasB using 2-Aminobenzoyl-AlaGly-Leu-Ala-4-Nitrobenzylamide as fluorogenic substrate preincubated for 15 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetElastase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips) - Helmholtz Centre For Infection Research (Hzi

Curated by ChEMBL
LigandPNGBDBM50542679(CHEMBL4639584)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa PA14 LasB elastase preincubated for 15 mins followed by substrate addition and measured after 60 mins using 2-am...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetVIM-1 metallo-beta-lactamase(Pseudomonas aeruginosa (g-Proteobacteria))
Xihua University

Curated by ChEMBL
LigandPNGBDBM50542679(CHEMBL4639584)
Affinity DataIC50: 860nMAssay Description:Inhibition of VIM1 (unknown origin) using fluorocillin as substrate by measuring difluoro-fluorescein formed using fluorescence plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Xihua University

Curated by ChEMBL
LigandPNGBDBM50542679(CHEMBL4639584)
Affinity DataIC50: 650nMAssay Description:Inhibition of NDM1 (unknown origin) using fluorocillin as substrate by measuring difluoro-fluorescein formed using fluorescence plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed