BDBM50541360 CHEMBL4640859

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1cccc2c1cccc2)CS[C@H](Cc3ccccc3)C(=O)NCCc4cccnc4

InChI Key InChIKey=GBALYMNAVPEZPA-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50541360   

TargetCytochrome P450 3A4(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50541360(CHEMBL4640859)
Affinity DataIC50: 75nMAssay Description:Inhibition of human full length CYP3A4 assessed using 7-benzyloxy-4 (trifluoromethyl)coumarin as substrate preincubated for 2 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)