BDBM50540012 CHEMBL4637520

SMILES CS(=O)(=O)c1ncn2c(NCc3c4CCOc4ccc3F)ncc(-c3ccc(nc3)C3CC3)c12

InChI Key InChIKey=BMLWIABJRSYZDK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50540012   

TargetPolycomb protein EED(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50540012(CHEMBL4637520)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of EED ( 1 to 441 residues) (unknown origin) pre-incubated for 15 mins before biotin-H3K27me3 (19 to 33 residues) addition and further inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed