BDBM50539784 CHEMBL1096940

SMILES COc1cc(O)c([C@@H]2CC(=O)c3c(O)cc(O)cc3O2)cc1C/C=C(\C)CCC=C(C)C

InChI Key InChIKey=CZVSHXUUSIQWSO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50539784   

TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rabbit)
Centre of Experimental Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50539784BDBM50539784(CHEMBL1096940)
Affinity DataIC50: 3.56E+4nMAssay Description:Inhibition of SERCA1 in NewZealand rabbit skeletal muscle SR vesicles using ATP as substrate incubated for 2 mins followed by Ca2+ addition by NADH c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rat)
Centre of Experimental Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50539784BDBM50539784(CHEMBL1096940)
Affinity DataIC50: 6.48E+4nMAssay Description:Inhibition of SERCA1 in rat INS-1E cells assessed as reduction in cell viability incubated for 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed