BDBM50533167 CHEMBL4572115

SMILES CCOc1cncc(Oc2cc(NC(=O)NC)ncc2-c2ccc(OCCO)nc2)c1

InChI Key InChIKey=UBGFEQNFPUGRSW-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50533167   

TargetHexokinase-4(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50533167BDBM50533167(CHEMBL4572115)
Affinity DataEC50:  660nMAssay Description:Activation of human recombinant glucokinase using 5 mM glucose monitored over 5 mins in presence of NAD+ by glucose 6-phosphate dehydrogenase coupled...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50533167BDBM50533167(CHEMBL4572115)
Affinity DataEC50:  660nMAssay Description:Activation of human recombinant glucokinase using 5 mM glucose monitored over 5 mins in presence of NAD+ by glucose 6-phosphate dehydrogenase coupled...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50533167BDBM50533167(CHEMBL4572115)
Affinity DataEC50:  1.30E+3nMAssay Description:Activation of human recombinant glucokinase using 5 mM glucose monitored over 5 mins in presence of NAD+ and glucose 6-phosphate 4% human serum album...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50533167BDBM50533167(CHEMBL4572115)
Affinity DataEC50:  1.30E+3nMAssay Description:Activation of human recombinant glucokinase using 5 mM glucose monitored over 5 mins in presence of NAD+ and glucose 6-phosphate 4% human serum album...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed