BDBM50532271 CHEMBL1236703

SMILES CCCc1c2c(n(n1)C)C(=O)NC(=N2)c3cc(sc3OCC)S(=O)(=O)N

InChI Key InChIKey=FENWRHVHBZQJGW-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50532271   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50532271(CHEMBL1236703)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human PDE5A1 catalytic domain (535 to 860 residues) expressed in Escherichia coli BL21-CodonPlus(DE3) cells using [3H]cGMP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50532271(CHEMBL1236703)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human PDE5A1 catalytic domain (535 to 860 residues) expressed in Escherichia coli BL21-CodonPlus(DE3) cells using [3H]cGMP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)