BDBM50532270 CHEMBL1236215

SMILES CSC1=Nc2ccccc2C(=O)N1c3c(cccc3F)F

InChI Key InChIKey=BFNBJSXMXXQLAW-UHFFFAOYSA-N

Data  7 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50532270   

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50532270(CHEMBL1236215)
Affinity DataIC50: 510nMAssay Description:Inhibition of recombinant human PDE7A1 catalytic domain (130 to 482 residues) expressed in Escherichia coli BL21-CodonPlus cells using [3H]cAMP as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50532270(CHEMBL1236215)
Affinity DataIC50: 510nMAssay Description:Inhibition of recombinant human PDE7A1 catalytic domain (130 to 482 residues) expressed in Escherichia coli BL21-CodonPlus cells using [3H]cAMP as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50532270(CHEMBL1236215)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of PDE4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50532270(CHEMBL1236215)
Affinity DataIC50: 510nMAssay Description:Inhibition of PDE7A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50532270(CHEMBL1236215)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of PDE4D2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50532270(CHEMBL1236215)
Affinity DataIC50: 510nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50532270(CHEMBL1236215)
Affinity DataIC50: 3.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed