BDBM50532264 CHEMBL4453729

SMILES Cc1nc2cc(ccc2s1)OCc3ccc4ccccc4n3

InChI Key InChIKey=DZPJYJCYZZYODA-UHFFFAOYSA-N

Data  2 KI

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50532264   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50532264(CHEMBL4453729)
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of human N-terminal His6-tagged PDE10A2 catalytic domain expressed in Escherichia coli BL21(DE3) RIL cells using 3',5'-cGMP as substrate b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50532264(CHEMBL4453729)
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of human N-terminal His6-tagged PDE10A2 catalytic domain expressed in Escherichia coli BL21(DE3) RIL cells using 3',5'-cGMP as substrate b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)