BDBM50531001 CHEMBL4446995

SMILES COC(=O)C1=C(NC(=N[C@H]1c2ccc(cc2Cl)F)c3nccs3)CN4CC(C[C@H]4C(=O)O)(F)F

InChI Key InChIKey=PEWCUEKNYZSVSW-UHFFFAOYSA-N

Data  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50531001   

TargetCapsid protein(HBV)
TBA

Curated by ChEMBL
LigandPNGBDBM50531001(CHEMBL4446995)
Affinity DataEC50:  3nMAssay Description:Inhibition of capsid in HBV infected in human HepG.2.2.15 cells assessed as reduction of HBV DNA incubated for 5 days by quantitative PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCapsid protein(HBV)
TBA

Curated by ChEMBL
LigandPNGBDBM50531001(CHEMBL4446995)
Affinity DataEC50:  3nMAssay Description:Inhibition of capsid in HBV infected in human HepG.2.2.15 cells assessed as reduction of HBV DNA incubated for 5 days by quantitative PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)