BDBM50529558 CHEMBL4456056

SMILES CC(=O)c1ccc(cc1)N2CCN(CC2)C(=O)NCc3ccc(nc3)OC

InChI Key InChIKey=IWZIKMPFQUSSMX-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50529558   

TargetProtein ENL(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50529558(CHEMBL4456056)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of C-terminal His6-tagged MLLT1 YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli Rosetta by alphascreen ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProtein ENL(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50529558(CHEMBL4456056)
Affinity DataKd:  5.50E+3nMAssay Description:Binding affinity to C-terminal His6-tagged MLLT1 YEATS domain (1 to 148 residues) (unknown origin) expressed in Escherichia coli Rosetta by isotherma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)