BDBM50529350 CHEMBL4546918

SMILES c1ccc2c(c1)C(=O)N(C2=O)Cc3ccc(cc3)NC(=O)N4CC(C4)c5cccnc5

InChI Key InChIKey=BXJQNJNBPGVHBT-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50529350   

TargetNicotinamide phosphoribosyltransferase(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50529350(CHEMBL4546918)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of full length recombinant human NAMPT using N15-NAM as substrate preincubated for 15 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)