BDBM50527797 CHEMBL4435863

SMILES Cc1c2cc(ccc2sc1S(=O)(=O)Nc3cccc(c3)CN)Cl

InChI Key InChIKey=OMVVAHZLDYMIPY-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50527797   

TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50527797(CHEMBL4435863)
Affinity DataIC50: 310nMAssay Description:Inhibition of hexahistidine-SUMO tagged Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21(DE3) at preincubated for 10 mins with NADH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50527797(CHEMBL4435863)
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant hexaHis-SUMO tagged Mycobacterium tuberculosis InhA expressed in Escherichia coli BL21 (DE3) incubated for 10 mins by color...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)