BDBM50524868 CHEMBL4552396

SMILES c1ccc(cc1)N2CC[C@@](C2=O)(C(=O)NCc3cc(cc(c3)Cl)F)O

InChI Key InChIKey=GYXUHDDOWYYRFT-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50524868   

TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524868(CHEMBL4552396)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)