BDBM50523230 CHEMBL4566973

SMILES c1ccc2c(c1)C(=O)C(=C(C2=O)O)Nc3ccc(cc3)F

InChI Key InChIKey=AVGHWZUEYVXFON-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50523230   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50523230(CHEMBL4566973)
Affinity DataIC50: 330nMAssay Description:Inhibition of human DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Blood fluke)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50523230(CHEMBL4566973)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Schistosoma mansoni DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)