BDBM50520631 Ametantrone

SMILES c1ccc2c(c1)C(=O)c3c(ccc(c3C2=O)NCCNCCO)NCCNCCO

InChI Key InChIKey=FFGSXKJJVBXWCY-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50520631   

TargetDNA topoisomerase 2-beta(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50520631(Ametantrone)
Affinity DataIC50: 30nMAssay Description:Poison activity at recombinant human topoisomerase 2beta using pBR322 plasmid as substrate after 30 mins by ethidium bromide staining based agarose g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)