BDBM50520460 CHEMBL4549501

SMILES c1cc(ccc1C#N)NC(=S)NCc2cnc3n2c(cs3)C#CC4CC4

InChI Key InChIKey=OROIVWMQNZZDMT-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50520460   

TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50520460(CHEMBL4549501)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant full-length N-terminal His-tagged human IDO1 (1 to 403 residues) expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50520460(CHEMBL4549501)
Affinity DataIC50: 16nMAssay Description:Inhibition of human IDO1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)