BDBM50514980 CHEMBL4438255

SMILES c1ccc(cc1)CC(=O)Nc2nnc(s2)N[C@@H]3CCN(C3)c4nnc(s4)N

InChI Key InChIKey=XEPCFWCPQXKTNL-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50514980   

TargetGlutaminase kidney isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514980(CHEMBL4438255)
Affinity DataIC50: 347nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutaminase liver isoform, mitochondrial(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514980(CHEMBL4438255)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed