BDBM50514211 CHEMBL4515030

SMILES c1cc2c(cc1C(=O)O)N(C[C@@]3(CCCc4c3ccc(c4)Cl)CO2)CC5CCC5

InChI Key InChIKey=UZONKUOJBLOPMC-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50514211   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
TBA

Curated by ChEMBL

LigandBDBM50514211(CHEMBL4515030)Copy SMILESCopy InChI

Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/21/2021
Entry Details Article
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