BDBM50514122 CHEMBL4548694

SMILES C[C@H](CC(=O)N1CCC(CC1)(CN2C=Nc3cc(ccc3C2=O)NC(=O)CCN4CCN(CC4)C)O)c5ccccc5

InChI Key InChIKey=QLBYDWATOPNXBG-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50514122   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50514122(CHEMBL4548694)
Affinity DataIC50: 90nMAssay Description:Inhibition of human full-length USP7 (1 to 1102 amino acids) expressed in Escherichia coli BL21(DE3) incubated 30 mins by Ubiquitin-AMC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50514122(CHEMBL4548694)
Affinity DataIC50: 90nMAssay Description:Inhibition of human USP7 using Ub-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50514122(CHEMBL4548694)
Affinity DataIC50: 190nMAssay Description:Inhibition of human USP7 using Ub-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)