BDBM50510995 CHEMBL4556229

SMILES c1ccc2c(c1)C(=O)c3c(cc(c(c3C2=O)N)N4CCN(CC4)C5CCCCC5)Nc6ccc(cc6)C(=O)O

InChI Key InChIKey=YLGUWQFLCMWHDK-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50510995   

TargetBDNF/NT-3 growth factors receptor(Human)
Osaka Prefecture University

Curated by ChEMBL
LigandPNGBDBM50510995(CHEMBL4556229)
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition of wild type human N-terminal GST-fusion tagged TRKB kinase domain (456 to 822 residues) expressed in baculovirus expression system by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Osaka Prefecture University

Curated by ChEMBL
LigandPNGBDBM50510995(CHEMBL4556229)
Affinity DataIC50: 199nMAssay Description:Inhibition of wild type human His-tagged TRKA kinase domain (441 to 796 residues) expressed in baculovirus expression system by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)