BDBM50508025 CHEMBL4535758

SMILES COc1cc2c(cc1OC)ncnc2C3CCN(CC3)C(=O)c4ccc(cc4)OC(F)(F)F

InChI Key InChIKey=SRRBAUZQZOASOY-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50508025   

TargetMitogen-activated protein kinase 7(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50508025(CHEMBL4535758)
Affinity DataIC50: 270nMAssay Description:Inhibition of His-tagged MAP2K5 activated N-terminal GST-tagged recombinant human ERK5 (1 to 398 residues) expressed in Escherichia coli using biotin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)