BDBM50506585 CHEMBL4515358

SMILES C[C@@H]1CN(Cc2c1n(nc2C(=O)Nc3cccc(c3)[C@@H](C)O)Cc4ccc(cc4)F)C(=O)c5ccc[nH]5

InChI Key InChIKey=IVFDDVKCCBDPQZ-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50506585   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
TBA

Curated by ChEMBL

LigandBDBM50506585(CHEMBL4515358)Copy SMILESCopy InChI

Affinity DataIC50: 120nMAssay Description:Inhibition of C-terminal 8-His tagged wild type human IDH1 (1 to 414 residues) expressed in Escherichia coli BL21(DE3)-T1R preincubated for 15 mins u...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/19/2021
Entry Details Article
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