BDBM50503349 CHEMBL4476817

SMILES [H]/N=C(/N)\Nc1cc(cc(c1)C(F)(F)F)C2CCNCC2

InChI Key InChIKey=SVJLJEMEWHBCNB-UHFFFAOYSA-N

Data  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503349   

TargetTyrosine-protein phosphatase non-receptor type 5(Human)
Beckman Research Institute of The City of Hope

Curated by ChEMBL
LigandPNGBDBM50503349(CHEMBL4476817)
Affinity DataKd:  8.00E+5nMAssay Description:Binding affinity to human STEP PTP domain (281 to 563 residues) expressed in Escherichia coli BL21(DE3) by ITCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 5(Human)
Beckman Research Institute of The City of Hope

Curated by ChEMBL
LigandPNGBDBM50503349(CHEMBL4476817)
Affinity DataKd:  3.80E+4nMAssay Description:Binding affinity to human 15N-labeled STEP PTP domain (281 to 563 residues) expressed in Escherichia coli OD2 by 1H,15N TROSY NMR spectral analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)