BDBM50503150 EVT-101

SMILES Cc1nccn1Cc1cc(cnn1)-c1ccc(F)c(c1)C(F)F

InChI Key InChIKey=BOVUHBFXPNLTKF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503150   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503150(EVT-101)
Affinity DataIC50: 12nMAssay Description:Negative allosteric modulation of GluN2B receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503150(EVT-101)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at NMDA receptor NR2B subunit (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed