BDBM50503135 CHEMBL4536755

SMILES c1ccc(cc1)[C@H](CN2[C@@H](CCN3C2=NC(=CC3=O)N4CCOCC4)C(F)(F)F)O

InChI Key InChIKey=PZFUMOISBVVUGC-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503135   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM50503135(CHEMBL4536755)Copy SMILESCopy InChI

Affinity DataIC50: 3nMAssay Description:Inhibition of Vps34 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/18/2021
Entry Details Article
Copy Entry DOIPubMedPDB3D Structure (crystal)
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM50503135(CHEMBL4536755)Copy SMILESCopy InChI

Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of PI3K p110alpha (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/18/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL