BDBM50503132 CHEMBL4586628

SMILES C[C@@H]1COCCN1C2=CC(=O)N3CC[C@H](N(C3=N2)CC(=O)C(C)C)C(F)(F)F

InChI Key InChIKey=ITCIAOUZMPREOO-UHFFFAOYSA-N

Data  7 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50503132   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503132(CHEMBL4586628)
Affinity DataIC50: 2nMAssay Description:Inhibition of Vps34 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503132(CHEMBL4586628)
Affinity DataIC50: 82nMAssay Description:Inhibition of Vps34 (unknown origin) by GFP-FYVE detection based cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase mTOR(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50503132(CHEMBL4586628)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM50503132(CHEMBL4586628)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of PI3K p110beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM50503132(CHEMBL4586628)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PI3K p110gamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM50503132(CHEMBL4586628)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3K p110delta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM50503132(CHEMBL4586628)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of PI3K p110alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed