BDBM50503083 CHEMBL4583926

SMILES CC[C@@H]1C(=O)N(c2cnc(nc2N1C3CCCC3)N(C)c4ccc(cc4OC)C(=O)NC5CCN(CC5)C)C

InChI Key InChIKey=ZDNOQFYOJHNBGG-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503083   

TargetBromodomain-containing protein 4(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50503083(CHEMBL4583926)
Affinity DataIC50: 100nMAssay Description:Displacement of Bio-JQ1 from recombinant human His6 tagged BRD4 bromodomain 1 by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTranscription initiation factor TFIID subunit 1(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50503083(CHEMBL4583926)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of biotinylated probe from human TAF1 bromodomain 2 (1522 to 1656 residues) expressed in Escherichia coli BL21 (DE3) by alphascreen assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed