BDBM50502434 CHEMBL4551647

SMILES CCCOC(=O)N1CCN(CC1)C(=O)c1ccc2c(Cl)cc(nc2c1)-c1ccccc1

InChI Key InChIKey=KSURKAFQFJOCBC-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50502434   

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandPNGBDBM50502434(CHEMBL4551647)
Affinity DataIC50: 300nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandPNGBDBM50502434(CHEMBL4551647)
Affinity DataKi:  3.90E+3nMAssay Description:Irreversible inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed