BDBM50501302 CHEMBL3985848

SMILES Cc1c2cc(ccc2c(cc1Oc3ccccc3OCCN4C=CC(=O)NC4=O)CC5CC5)C#N

InChI Key InChIKey=VAFJQCGXOLTBQY-UHFFFAOYSA-N

Data  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50501302   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50501302(CHEMBL3985848)
Affinity DataEC50:  900nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant infected in human MT2 cells assessed as protection against viral infection by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50501302(CHEMBL3985848)
Affinity DataEC50:  1.20E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant infected in human MT2 cells assessed as protection against viral infection by MTT ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)