BDBM50500194 CHEMBL3746716

SMILES c1ccc(cc1)[C@H](c2cc3ccccc3o2)NS(=O)(=O)c4ccc5c(c4)OCCCO5

InChI Key InChIKey=KMUUQMAWJDDNPP-UHFFFAOYSA-N

Data  1 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50500194   

TargetGlucokinase regulatory protein(Mouse)
Amgen

Curated by ChEMBL
LigandPNGBDBM50500194(CHEMBL3746716)
Affinity DataEC50: >1.25E+4nMAssay Description:Inhibition of glucokinase-GKRP binding interaction in mouse hepatocytes assessed as induction of glucokinase translocationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetGlucokinase regulatory protein(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50500194(CHEMBL3746716)
Affinity DataIC50: 870nMAssay Description:Binding affinity to human biotinylated AviTag GKRP assessed as inhibition of protein interaction with fluorescein tagged human glucokinase by AlphaSc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)