BDBM50497030 CHEMBL3233203

SMILES Cc1ccc(cc1)C(=O)CSc2[nH]c3c(n2)N=C(NC3=O)N

InChI Key InChIKey=HIGGTDYQNPXEFT-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50497030   

Target2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase(Escherichia coli (strain K12))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50497030(CHEMBL3233203)
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibition of GST-tagged Escherichia coli HPPK expressed in Escherichia coli using 6-hydroxymethyl-7,8-dihydropterin hydrochloride as substrate after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase(Escherichia coli (strain K12))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50497030(CHEMBL3233203)
Affinity DataKd:  6.70E+3nMAssay Description:Binding affinity to GST-tagged Escherichia coli HPPK expressed in Escherichia coli by SPR assay based alternative equilibrium affinity method in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)