BDBM50491987 CHEMBL2391618

SMILES c1c2c(cc(c1OC[C@@H]3CCNC3)Cl)C(=O)NC=C2

InChI Key InChIKey=RCMBOTAAIQVYEO-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50491987   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Sanofi

Curated by ChEMBL

LigandBDBM50491987(CHEMBL2391618)Copy SMILESCopy InChI

Affinity DataIC50: 1.57E+5nMAssay Description:Inhibition of MEK1 (unknown origin) using ATP and ERK2 K54R as substrate after 60 to 80 mins by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
9/1/2020
Entry Details Article
Copy Entry DOIPubMedPDB3D Structure (crystal)
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