BDBM50491984 CHEMBL2391619

SMILES c1cc(c2c(c1)[nH]nc2N)C#N

InChI Key InChIKey=KVXRKRURRSOVSJ-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50491984   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Sanofi

Curated by ChEMBL

LigandBDBM50491984(CHEMBL2391619)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of MEK1 (unknown origin) using ATP and ERK2 K54R as substrate after 60 to 80 mins by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidPDBSimilars

In Depth
Date in BDB:
9/1/2020
Entry Details Article
Copy Entry DOIPubMedPDB3D Structure (crystal)
Copy Rxn URL